Indications
Dietary supplements, Iron deficiency, Iron deficiency anemia, Pregnancy, Pregnancy and lactation
Therapeutic Class
Pharmacology
Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin.
Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy.
Dosage & Administration
One capsule daily. In more severe cases, 2 capsules a day may be required or as directed by the physician.
Interaction
Carbonyl iron: Antacids may decrease the absorption of carbonyl iron.
Folic acid: Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations.
Contraindications
Side Effects
Iron: Constipation, Diarrhea, Nausea, Epigastric pain, Dark stools, Vomiting Frequency Not Defined Hemosiderosis (during long-term administration of large amounts),Urine discoloration,Dental stain by some formulations,Heartburn
Folic acid: Bronchospasm, Erythema, Malaise, Pruritus, Rash, Slight flushing
Pregnancy & Lactation
Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.
Lactation: Excreted in breast milk